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. Author manuscript; available in PMC: 2021 Jan 14.
Published in final edited form as: ACS Infect Dis. 2020 Jun 9;6(7):1587–1598. doi: 10.1021/acsinfecdis.9b00515

Figure 1.

Figure 1.

Maltodextrin transporter-targeted fluorescent and PET probes published from the Murthy group, highlighting the synergy between optical imaging and PET. (A) Data obtained using the MDP-2 NIR probe in a simple preclinical model of bacterial infection, in which fluorescent signal is seen in living E. coli but not in LPS-induced inflammation in the opposite flank (adapted from Ning et al. 2011). (B) Similar findings for the MH18F maltohexose-derived positron emission tomography tracer (adapted from Ning et al. 2014).