Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 10;162(2):641–652. doi: 10.1097/j.pain.0000000000002064

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a “work of the United States Government” for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of employees of the Federal Government.

PMC Copyright notice

Figure 4. — Neural placebo analgesic effects. (A) Pain-related activations in response to the same temperature stimulus during the control cream condition (red) and placebo cream condition (blue) compared to baseline (overlapping regions displayed in purple). (B) Significant placebo-related reductions (“placebo effect”, control > placebo) in brain activity were observed across all participants within the right midanterior and posterior insula and bilateral S2. Inset: The HC and FM patient contrast of parameter estimates for the placebo-modulated S2 and insula regions. All results are presented at a voxel-based threshold of z > 2.3, cluster correction of P < 0.05. ant, anterior; FM, fibromyalgia; HC, healthy controls; Ins, insula; L, left; post, posterior; R, right; S2, secondary somatosensory cortex.