Table 1.

Precision–recall values for prediction of PTx-binding according to paratyping and clonotyping at the optimal thresholds of 75% and 72%, respectively

Method	Sequence identity threshold	Precision	Recall
Paratyping	75%	84%	76%
Clonotyping	72%	83%	79%

Sequence identity is calculated across the predicted paratope for paratyping and across the CDRH3 for clonotyping. The methods behave comparably over the full precision–recall curve. These thresholds were then used for the prospective repertoire mining experiment.