Table 3.
Cox analysis of mortality
| HR | 95% CI for HR | p | ||
|---|---|---|---|---|
| Lower | Upper | |||
| Age (Year) | 1.022 | 1.003 | 1.041 | 0.025 |
| COVID-19 disease severity* | 6.223 | 2.168 | 17.863 | 0.001 |
| Congestive heart failure | 2.247 | 1.228 | 4.111 | 0.009 |
| AST (> 2 × upper limit of normal) during hospitalization | 3.909 | 2.143 | 7.132 | < 0.001 |
| Thrombocytopenia (< 150 × 109/L) during hospitalization | 1.864 | 1.025 | 3.390 | 0.041 |
| Anaemia (Hgb < 10 g/dl) during hospitalization | 0.541 | 0.284 | 1.029 | 0.061 |
| CRP (mg/L)** | 1.767 | 0.890 | 3.507 | 0.104 |
| Ferritin (ng/L) | 1.057 | 1.006 | 1.111 | 0.028 |
* Severe-Critical Disease/ Mild-Moderate Disease ** ≥10 times increase/ < 10 times increase
Abbreviations; COVID-19, coronavirus disease 2019; AST, aspartate aminotransferase; Hgb, Haemoglobin; CRP, C-reactive protein
The following variables were included in the model, which were found to be associated with mortality in univariate analyses: Age, gender, COVID-19 related clinic presentation at the time of diagnosis, congestive heart failure, chronic obstructive pulmonary disease, time between first symptom-diagnosis, diagnosis with nasopharyngeal swab PCR test, diagnosis with radiological test, lymphocyte, platelet count, CRP level, serum albumin and ferritin at admission, AST (> 2 × upper limit of normal), LDH (> 2 × upper limit of normal), lymphopenia (< 1.5 × 109 /L), anaemia (Hgb < 10 g/dl) and thrombocytopenia (< 150 × 109/L) during hospitalization, computed tomography (CT) findings