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. Author manuscript; available in PMC: 2021 Jan 14.
Published in final edited form as: FASEB J. 2020 Jul 21;34(9):12024–12039. doi: 10.1096/fj.201902826RR

Figure 1. UBAP2 is a novel regulator of macropinocytosis.

Figure 1.

(A and B)UBAP2 silencing decreased TMR-dextran uptake in pancreatic cancer cells. Top, silencing UBAP2 by siRNA or shRNA in pancreatic cancer cells including AsPC1 (A), Panc04.03 and PANC1 (B). Below are the corresponding, TMR-dextran uptake (red) assay indicated that depletion of UBAP2 decreased macropinocytosis. Nuclei (blue) were stained by DAPI. Scale bar, 10 μm. Bottom, Quantification of dextran uptake. Mean ± SD; **, p<0.01; *, p<0.05.