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. Author manuscript; available in PMC: 2021 Jan 14.
Published in final edited form as: FASEB J. 2020 Jul 21;34(9):12024–12039. doi: 10.1096/fj.201902826RR

Figure 4. UBAP2 promotes pancreatic tumor growth in vivo in mice.

Figure 4.

(A) UBAP2 silencing decreased proliferation, migration and invasion in pancreatic cancer cells. (B) Tumor growth was monitored by non-invasive bioluminescence analysis. (C) Final tumor mass of the mice showed that knockdown of UBAP2 significantly decreased the tumor growth. Each group contains 7 mice. N=7. *p < 0.05. (D) In vivo macropinocytosis uptake assay and quantification. Section of TMR-dextran (red)-injected mouse xenograft tumors were stained with anti-CK19 (green). Quantification of dextran uptake in (right panel). Scale bar, 10 μm. **p<0.01, N=4.