Table 1.
Functional annotation and signaling pathway analysis of the selected DEGs in patients with HCC.
| Category | ID | Description | Count | P value |
| GOTERM-BP | GO:0002576 | Platelet degranulation | 4 | .012227934 |
| GO:0051092 | Positive regulation of NF-kappaB transcription factor activity | 4 | .024016725 | |
| GO:0032760 | Positive regulation of tumor necrosis factor production | 3 | .020119064 | |
| GO:2001237 | Negative regulation of extrinsic apoptotic signaling pathway | 3 | .013439698 | |
| GO:0030031 | Cell projection assembly | 2 | .027552817 | |
| GO:0048739 | Cardiac muscle fiber development | 2 | .036569485 | |
| GO:0045410 | Positive regulation of interleukin-6 biosynthetic process | 2 | .036569485 | |
| GOTERM-CC | GO:0005737 | Cytoplasm | 39 | .001153533 |
| GO:0005829 | Cytosol | 23 | .048863848 | |
| GO:0070062 | Extracellular exosome | 21 | .032205588 | |
| GO:0005654 | Nucleoplasm | 21 | .02939589 | |
| GO:0005925 | Focal adhesion | 8 | .002329729 | |
| GO:0005856 | Cytoskeleton | 6 | .029708087 | |
| GO:0030027 | Lamellipodium | 4 | .038894882 | |
| GO:0000786 | Nucleosome | 4 | .009675674 | |
| GO:0030018 | Z disc | 4 | .017793733 | |
| GO:0031093 | Platelet alpha granule lumen | 3 | .027213685 | |
| GOTERM-MF | GO:0005515 | protein binding | 52 | .030780429 |
| GO:0044822 | poly (A) RNA binding | 11 | .043200361 | |
| GO:0008307 | structural constituent of muscle | 3 | .017293809 | |
| KEGG_PATHWAY | hsa04510 | Focal adhesion | 6 | .005150245 |
| hsa04810 | Regulation of actin cytoskeleton | 5 | .027691493 | |
| hsa04540: | Gap junction | 4 | .01235768 | |
| hsa04611 | Platelet activation | 4 | .034401252 |
BP = biological process, CC = cellular component, DEGs = differentially expressed genes, GO = gene ontology, HCC = hepatocellular carcinoma, KEGG = Kyoto Encyclopedia of Genes and Genomes, MF = molecular function.