Table 1.

The demographic and clinicopathological characteristics of the primary and validation Cohorts.

Variable	Primary Cohort	Validation Cohort	P-value
Age, yr	60 (50,70)	60 (50,70)	.754
Race, N (%)			.525
White	8129 (78.3)	3424 (77.9)
Black	1523 (14.7)	639 (14.5)
Other	725 (7.0)	330 (7.5)
Male, N (%)	5239 (50.5)	2207 (50.2)	.783
Differentiation, N (%)			.761
Well	7034 (67.8)	3005 (68.4)
Moderately	1787 (17.2)	741 (16.9)
Poorly	1556 (15.0)	647 (14.7)
Radiation, yes, N (%)	209 (2.0)	69 (1.6)	.040
Chemotherapy, yes, N (%)	1327 (12.8)	583 (13.3)	.424
Tumour location, N (%)			.813
Cecum	559 (5.5)	234 (5.3)
Small Intestine	3430 (33.1)	1413 (32.2)
Pancreas	2461 (23.7)	1062 (24.2)
Rectum	1509 (14.5)	650 (14.8)
Stomach	810 (7.8)	327 (7.4)
Colon	528 (5.1)	227 (5.2)
Appendix	1070 (10.3)	480 (10.9)
Stage, N (%)			.668
Localized	5014 (48.3)	2117 (48.2)
Distant	2469 (23.8)	1073 (24.4)
Regional	2894 (27.9)	1203 (27.4)
Tumour size			.109
<2cm	5514 (53.1)	2273 (51.7)
2–4cm	2923 (28.2)	1236 (28.1)
>4cm	1940 (18.7)	884 (20.1)
T staging, N (%)			.394
T0	63 (0.6)	24 (0.5)
T1	3816 (36.8)	1602 (36.5)
T2	2044 (19.7)	859 (19.6)
T3	2868 (27.6)	1246 (28.4)
T4	1392 (13.4)	601 (13.7)
Tx	194 (1.9)	61 (1.4)
N staging, N (%)			.659
N1	10314 (99.4)	4369 (99.5)
N0	63 (0.6)	24 (0.5)
M staging, N (%)			.919
M1	2156 (20.8)	916 (20.9)
M0	8221 (79.2)	3477 (79.1)
Marital status at diagnosis			.574
Single	1928 (18.6)	843 (19.2)
Marry	6444 (62.1)	2674 (60.9)
Widowed	951 (9.2)	413 (9.4)
Divorced	1054 (10.2)	463 (10.5)
Survival time, month	32 (16,53)	31 (16,52)	.066
Survival status, dead, N (%)	2559 (24.7)	1080 (24.6)	.922

Other race: American Indian/AK Native, Asian/Pacific Islander.