Table 3.

Incidence of adverse events during treatment.

Adverse event	HIFU alone (n = 30)	CEUS+HIFU (n = 34)	P
Sacrococcygeal pain	5/30 (16.7%)	4/34 (11.8%)	.573
Skin burn	0/30 (0%)	0/34 (0%)	–
Pain in treatment zone	6/30 (20.0%)	8/34 (23.5%)	.733
Groin pain	1/30 (3.3%)	0/34 (0%)	.469
Sensation of rectal tenesmus	2/30 (6.7%)	1/34 (2.9%)	.482
Leg pain	1/30 (3.3%)	0/34 (0%)	.469

Data are presented as n/N (%). The following pain rating scale was used: 0 = painless; 1 to 2 = mild pain; 3 to 4 = moderate pain; 5 to 6 = severe pain; 7 to 8 = very severe pain; and 9 to 10 = unbearable pain. The pain score was <4 points in all patients.