Table 1. Baseline characteristics of children and adolescents stratified by baseline viral load suppression (N = 306).
| Characteristics | Total sampled | Baseline Viral load (copies/ml) | Unadjusted Odds Ratio (95% CI) | Adjusted Odds Ratio [95% CI] | p-value | ||
|---|---|---|---|---|---|---|---|
| Suppressed | Unsuppressed | ||||||
| <1000 | ≥1000 | ||||||
| N | 306 | 209(68%) | 97(32%) | ||||
|
Age group (years) |
<10 | 110 (36%) | 71(65%) | 39(35%) | - | - | |
| 10–14 | 107 (35%) | 79(74%) | 28(26%) | 1.55 [0.87–2.77] |
0.84 [0.38–1.85] |
0.669 | |
| 15–23 | 89 (29%) | 59(66%) | 30(34%) | 1.08 [0.60–0.94] |
0.52 [0.21–1.28] |
0.153 | |
|
Gender |
Female | 165 (54%) | 117(72%) | 48(28%) | - | ||
| Male | 141 (46%) | 92(64%) | 49(36%) | 0.77 [0.47–1.25] |
0.80 [0.49–1.30] |
0.368 | |
| HIV care center | Hospital | 84 (27%) | 61(73%) | 23(27%) | - | ||
| Outreach clinics | 222 (73%) | 147(66%) | 74(33%) | 0.75 [0.43–1.31] |
0.77 [0.43–1.36] |
0.367 | |
|
Caregiver |
Both parents | 34 (12%) | 24(71%) | 10(29%) | - | ||
| Single parent | 142 (51%) | 101(71%) | 41(29%) | 1.03 [0.45–2.34] |
|||
| Non-parent | 105 (37%) | 68(65%) | 37(35%) | 0.77 [0.33–1.77] |
|||
|
ART line |
First-line (NNRTI) | 296(97%) | 202(68%) | 94(32%) | - | ||
| Second-line (PI) (ATV/r or LPV/r) | 10 (3%) | 7(70%) | 3(30%) | 1.08 [0.27–4.29] |
|||
| ART regimen | NVP | 113(37%) | 69(61%) | 44(39%) | - | - | - |
| EFV | 183(60%) | 133(73%) | 50(27%) | 1.70 [1.03–2.79] |
2.44 [1.11–5.36] |
0.026 | |
| PI (ATV/r or LPV/r) | 10(3%) | 7(70%) | 3(30%) | 1.49 [0.37–6.06] |
2.18 [0.47–10.03] |
0.317 | |
| ART duration (years) | Median (IQR) |
5.2 (3.0–6.5) |
5.2 (2.8–6.5) |
5.2 (3.2–6.5) |
0.95 [0.86–1.05] |
||
|
CD4 (cells/cu mm) |
<500 | 47(31%) | 18(38%) | 29(62%) | - | - | |
| ≥500 | 106(69%) | 79(75%) | 27(25%) | 4.71 [2.26–9.81] |
|||
ART-Antiretroviral therapy, PI-Protease inhibitor, NNRTI-Non-nucleoside reverse transcriptase inhibitor, NVP-Nevirapine, EFV-Efavirenz, IQR-Interquartile range