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. 2021 Jan 14;16(1):e0245085. doi: 10.1371/journal.pone.0245085

Table 3. Factors associated with viral suppression of children and adolescents at follow-up (N = 257).

Characteristics Viral suppression n/N (%) Unadjusted Odds Ratio [95%CI] Adjusted Odds Ratio [95% CI] p-value
Overall 211/257(82.1%)
Switched to a PI
No 129/150 (86%) 1 1 -
Yes 82/107 (76.6%) 0.53 [0.28–1.02] 2.71 [0.99–7.44] 0.053
Baseline viral load
Failure (> = 1000 copies/ml) 52/82 (63.4%) 1 1 -
Suppressed (<1000 copies/ml) 159/175(90.9%) 5.73[2.90–11.35] 9.37 [3.62–24.26] <0.001
Age group (years)
<10 56/69 (81.2%) 1 1 -
10–14 76/86 (88.4%) 1.76 [0.72–4.31] 2.37 [0.83–6.77] 0.106
15–23 79/102 (77.5%) 0.80 [0.37–1.71] 1.00 [0.39–2.55] 0.997
Gender
Female 119/140 (85.0%) 1 1 -
Male 92/117 (78.6%) 0.65 [0.34–1.23] 0.83[0.40–1.70] 0.606
HIV care site
Hospital 104/131 (79.4%) 1 1 -
Outreach 107/126 (84.9%) 1.46 [0.77–2.79] 1.70 [0.80–3.358] 0.165
Caregiver
Both parents 23/31 (74.2%) 1 1 -
Single parent 104/123 (84.6%) 1.90 [0.74–4.88] 2.07 [0.71–6.02] 0.184
Non-parent 69/85 (81.2%) 1.50 [0.57–3.96] 1.86 [0.60–5.72] 0.280

CI- Confidence interval, PI-Protease inhibitor