Fig 5. The structural variants identified in the genomes of skin cells.

(A) The number of structural variants in each donor plotted against the ages of the donors. The black inclined line denotes the linear regression of the data, while the dotted curves denote the 95% confidence intervals. (B) The number of structural variants that were or were not within hotspots and common fragile sites. A Fisher’s exact test was performed to determine if structural variants in hotspots were also preferentially present within common fragile sites. (C) The types of structural variants that overlap and do not overlap common fragile sites. A Chi-square test was performed to determine if the structural variant types within common fragile sites were different from those that did not overlap common fragile sites. The source data for this figure are in S11 Table.