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. 2020 Dec 2;85(24):16226–16235. doi: 10.1021/acs.joc.0c01659

Table 2. Cytotoxicity (IC50, nM) of Ipomoeassin F and Its Analogues 2 and 3a.

  ring size MDA-MB-231 MCF7
2 22 1.8 ± 0.3 3.9 ± 0.7
ipomoeassin F 20 5.5 ± 0.6 13.4 ± 2.2
3 19 102.2 ± 9.8 445.1 ± 13.3
a

The data were obtained from at least three independent experiments.