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Patients with ER negative status and more advanced pathological AJCC Stage were more common in Grade 3 BCs in the all cohorts. Also, Grade 3 BCs were more prevalent in Basal, HER2, and Luminal B subtypes, compared to Luminal A subtype on PAM50 classification in the all cohorts (all p<0.001). Furthermore, Grade 3 BCs demonstrated higher gene expression of MKI67 (all p<0.001).
ER, estrogen receptor; AJCC, American Joint Committee for Cancer
