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Nottingham Grade 3 BCs demonstrated significantly higher pCR rate in response to NAC in the GSE25066 cohort (p<0.001). Other two cohorts (GSE22226 and GSE22358) also demonstrated trends towards higher pCR rate in Grade 3 tumors (p=0.06 and 0.09, respectively).
BC, Breast cancer; pCR, pathological complete response; NAC, neoadjuvant chemotherapy
