Identification of Distinct Developmental Trajectories toward NMPs and Anterior and Posterior Somitic-Cell Subsets
(A) UMAP layout from Pijuan-Sala et al. (2019) highlighting cells belonging to the developmental trajectories for anterior somitic tissues, the newly formed posterior somitic tissues, and NMPs present at E8.5, predicted using WOT analysis. For visualization purposes, the rare populations of shared ancestors were plotted on top.
(B) UMAP layout from Pijuan-Sala et al. (2019) highlighting the same cells as in (A) colored by sampling time point.
(C) Gene-expression dynamics along the three developmental trajectories reveals distinct transcriptional programs. y axis: mean log2 (normalised counts).
See also STAR Methods; Figure S2; Table S1.