TABLE 2.

Comparison of study objectives in different times

Variables	Before intervention		15 minutes		30 minutes		60 minutes		120 minute
	Intravenous	Nebulized	Intravenous	Nebulized	Intravenous	Nebulized	Intravenous	Nebulized	Intravenous	Nebulized
Mean arterial blood oxygen (mm Hg)	89.85 ± 4.12	90.3 ± 4.29	91.25 ± 3.46	91.35 ± 3.87	92.3 ± 3.20	92.6 ± 2.40	94.1 ± 1.72	95.05 ± 1.13	96.4 ± 1.33	95.8 ± 0.60
P‐Value	.634		.903		.637		.005		.012
Mean number of breaths per minute	30.7 ± 3.63	30.2 ± 6.07	29.45 ± 3.99	26.9 ± 5.30	27.2 ± 3.70	25.75 ± 4.84	24.35 ± 2.66	21.3 ± 2.95	20.55 ± 2.89	17.2 ± 1.48
P‐Value	.656		.017		.137		<.000		<.000
Mean severity of dyspnea	2.55 ± 0.50	2.45 ± 0.74	2.5 ± 0.59	2.45 ± 0.74	1.9 ± 0.84	1.75 ± 0.70	1.1 ± 0.63	1 ± 0.55	0.36 ± 0.48	0.35 ± 0.48
P‐Value	.486		.743		.391		.454		.868
Mean severity of sweating	1.75 ± 0.63	1.55 ± 0.67	1.45 ± 0.87	1.05 ± 0.98	0.7 ± 0.64	0.55 ± 0.67	0.25 ± 0.43	0.1 ± 0.30	0	0
P‐Value	.176		.059		.315		.08		‐
Mean severity of crackles	2.2 ± 0.68	2.25 ± 0.43	2.2 ± 0.68	2.25 ± 0.43	2 ± 0.55	1.95 ± 0.50	1.3 ± 0.85	1.25 ± 0.43	0.95 ± 0.81	0.85 ± 0.36
P‐Value	.699		.699		.674		.743		.481
Mean heart rate (bpm)	97.45 ± 11.41	93.5 ± 19.46	97.8 ± 9.17	91.9 ± 16.28	93.45 ± 8.11	89.7 ± 15.07	87.8 ± 6.36	84.2 ± 12.64	84.85 ± 3.93	83.8 ± 10.79
P‐Value	.272		.049		.17		.113		.566
Mean systolic blood pressure (mm Hg)	158.05 ± 30.18	144.55 ± 28.89	155.6 ± 26.39	144 ± 24.56	151.05 ± 23.21	139.6 ± 22.53	142.3 ± 17.84	135.5 ± 22.38	135.35 ± 21.47	131.95 ± 22.04
P‐Value	.044		.045		.028		.137		.487
Mean diastolic blood pressure (mm Hg)	94.15 ± 12.99	97.15 ± 18.20	91.55 ± 14.94	90.85 ± 24.05	91.55 ± 11.17	92.2 ± 21.10	86.85 ± 9.89	85.6 ± 18.65	83.2 ± 9.86	80.75 ± 15.61
P‐Value	.399		.876		.864		.71		.404