Table 3.

Concentration changes of ZJF active ingredients in rat serum after different treatment time (n = 3).

Dose	P t	Contents (ng/mL)
		Chlorogenic acid	Jatrorrhizine	Coptisine	Palmatine	Berberine	Evodin	Evodiamine	Rutaecarpine
ZJF-L (20 mg/kg)	6 h	1.96 ± 0.17	4.70 ± 0.46	3.75 ± 0.63	9.65 ± 0.82	59.95 ± 3.10	7.25 ± 0.75	0.99 ± 0.12	nd
	12 h	1.08 ± 0.19	2.09 ± 0.22	3.15 ± 0.37	3.10 ± 0.62	11.09 ± 1.17	2.86 ± 0.58	0.33 ± 0.06	nd
	24 h	1.13 ± 0.26	3.03 ± 0.46	1.78 ± 0.53	3.04 ± 0.62	3.87 ± 0.77	2.76 ± 0.47	0.15 ± 0.04	nd
ZJF-H (40 mg/kg)	6 h	3.85 ± 0.78	11.42 ± 0.71	9.33 ± 0.43	20.73 ± 1.55	100.28 ± 2.31	14.75 ± 1.26	2.64 ± 0.44	nd
	12 h	2.56 ± 0.81	4.04 ± 0.50	7.64 ± 0.60	6.50 ± 0.79	21.32 ± 1.89	6.74 ± 0.33	0.52 ± 0.07	nd
	24 h	2.74 ± 0.62	6.26 ± 0.95	3.97 ± 0.41	5.62 ± 0.94	6.30 ± 0.60	6.25 ± 0.94	0.23 ± 0.05	nd