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. 2021 Jan 7;2021:3075973. doi: 10.1155/2021/3075973

Table 1.

Effects of oral and rectal administration of different doses of QB extract (200, 400 mg/kg) and sulfasalazine (500 mg/kg) on colonic macroscopic damage (A) and histological score (B) rats' TNBS-induced colitis.

Group Macroscopic score Histological score
Sham control 0.55 ± 0.11 0.78 ± 0.09
Negative control 4.97 ± 0.26## 13.1 ± 0.48##
QB extract 200 mg/kg orally 3.04 ± 0.21##∗∗ 9.1 ± 0.37##∗∗
QB extract 400 mg/kg orally 2.17 ± 0.18##∗∗ 7.95 ± 0.26##∗∗
QB extract 200 mg/kg rectally 1.88 ± 0.33##∗∗ 7.23 ± 0.15##∗∗
QB extract 400 mg/kg rectally 1.43 ± 0.14##∗∗ 6.51 ± 0.22##∗∗
Sulfasalazine (treated control) 1.24 ± 0.16∗∗ 6.12 ± 0.41##∗∗

Data are expressed as means ± SEM. ##P < 0.01 vs. sham control; P < 0.05, ∗∗P < 0.01 vs. TNBS control.