Table 1.
Characteristics of the study participants.
| Total | Men | Women | P valuea | |
|---|---|---|---|---|
| Sample size | 13,288 | 7.782 | 5.506 | NA |
| Age, median (IQR), y | 53 (46–61) | 53 (46–61) | 53 (46–61) | 0.089 |
| Serum uric acid, Median (IQR), mg/dL | 5.21 (4.36–6.18) | 5.81 (5.04–6.67) | 4.44 (3.80–5.11) | < 0.001 |
| Hyperuricemiab, % | 13.9 | 17.9 | 8.2 | < 0.001 |
| Hypertensionc, % | 40.4 | 46.2 | 32.2 | < 0.001 |
| eGFR, median (IQR), mL/min/1.73 m2 | 79.5 (71.1–89.0) | 78.6 (70.5–87.3) | 81.0 (72.0–90.9) | < 0.001 |
| Reduced renal functiond, % | 5.5 | 5.9 | 4.9 | 0.018 |
| BMI, median (IQR), kg/m2 | 25.1 (23.0–27.3) | 25.8 (24.0–27.8) | 23.9 (22.0–26.1) | < 0.001 |
| FPG, median (IQR), mmol/L | 5.25 (4.89–5.83) | 5.35 (4.95–6.01) | 5.13 (4.80–5.59) | < 0.001 |
| TG, median (IQR), mmol/L | 1.25 (0.89–1.79) | 1.36 (0.97–1.94) | 1.13 (0.81–1.58) | < 0.001 |
| TC, median (IQR), mmol/L | 4.85 (4.29–5.48) | 4.77 (4.23–5.37) | 4.99 (4.40–5.65) | < 0.001 |
BMI, body mass index; eGFR, estimated glomerular filtration rate; IQR, interquartile range; NA, not applicable; FPG, fasting plasma glucose; TC, total cholesterol; TG, triglyceride.
aCompared between men and women. The Mann Whitney U was used for continuous variables and Fisher’s exact test was used for categorical variables.
bHyperuricemia was defined as uric acid ≥ 7 mg/dL for men and ≥ 6 mg/dL for women.
cHypertension was defined as systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg.
dReduced renal function was defined as eGFR < 60 mL/min/1.73 m2.