Table 2.
Functional annotation of a CDS (yellow border in Fig. 3Β).
| Annotation source | Accession | Function |
|---|---|---|
| Blast2Go | P: GO:0008616; F:GO:0046872; F:GO:0070497 | P: queuosine biosynthetic process; F:metal ion binding; F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity |
| COG Category | H | Coenzyme transport and metabolism |
| COG Function | COG0720 | 6-Pyruvoyl-tetrahydropterin synthase |
| EggNOG | PST_2317 | 6-Carboxy-5,6,7,8-tetrahydropterin synthase |
| EggNOGKegg | K01737 | queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] |
| Gene3D-4.2.0 | G3DSA:3.30.479.10 | 6-Pyruvoyl tetrahydropterin synthase/QueD |
| Interpro-72.0 | IPR007115 | 6-Pyruvoyl tetrahydropterin synthase/QueD family |
| KEGG Brite; KEGG Pathway | K09180; K09182 | –; Protein families: genetic information processing |
| KEGG Function | K03016 | Transfer RNA biogenesis [BR: ko03016] |
| KEGG Genes | K01737 | queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] |
| PANTHER Protein | PTHR12589:SF7 | None |
| Pfam InterPro | PF01242 | 6-Pyruvoyl tetrahydropterin synthase |
| PIRSF | PIRSF006113 | 6-Pyruvoyl tetrahydropterin synthase [Validated] |
| Prokka | Ref Seq: ABP79976.1 | 6-Pyruvoyl tetrahydrobiopterin synthase, putative |
| Rast FigFam | fig|316.409.peg.704 | 6-Carboxytetrahydropterin synthase (EC 4.1.2.50); Queuosine biosynthesis QueD, PTPS-I; KEGG_ENZYME:4.1.2.50 |
| Reactome | R-HSA-1474151; | Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, Homo sapiens |
| SUPERFAMILY | SSF55620 | Tetrahydrobiopterin biosynthesis enzymes-like |
| TIGRFAM | TIGR03367 | queuosine_QueD: queuosine biosynthesis protein QueD |