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. 2021 Jan 14;11:48. doi: 10.1038/s41398-020-01169-7

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© The Author(s) 2021

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Fig. 2 — Left: HYDRA identified two clusters of patients based on the adjusted Rand index (ARI). This is shown as a clear peak in ARI values for the 2-cluster solution. Right: The two clusters differed in global and regional cortical thickness; the Cohen’s d of these regional differences is mapped onto the corresponding cortical regions (additional details in Supplemental Material).