. 2021 Jan 14;11:1305. doi: 10.1038/s41598-020-80011-y

Table 3.

The activities of liver copper-zinc superoxide dismutase (CuZnSOD, U/g tissue), manganese superoxide dismutase (MnSOD, U/g tissue), catalase (CAT, μmol H₂O₂/min/g tissue), glutathione peroxidase (GSH-Px, μmol NADPH/min/g tissue), glutathione reductase (GR, nmol NADPH/min/g tissue) and glutathione S-transferase (GST, nmol GSH/min/g tissue), as well as liver concentrations of glutathione (GSH, nmol/g tissue), sulfhydryl groups (SH, nmol/g tissue), and lipid peroxides (TBARS, nmol/g tissue).

	S	S + M	I/R	I/R + M
CuZnSOD	6352 ± 157	6113 ± 121	3548 ± 171^a	5967 ± 133.164^b
MnSOD	3358 ± 74	4599 ± 134^a	1297 ± 48^a	2014 ± 37^ab
CAT	76,959 ± 2015	91,565 ± 2,706^a	77,272 ± 2,723	147,865 ± 5,002^ab
GSH-Px	72,172 ± 4408	74,382 ± 1,879	55,901 ± 3,113^a	14,320 ± 4,243^ab
GSH	4037 ± 241	6449 ± 209^a	1513 ± 99^a	3645 ± 95^ab
GR	7852 ± 275	8135 ± 377	17,126 ± 397^a	20,765 ± 654^ab
GST	27,369 ± 6190	29,007 ± 4,983	37,262 ± 5,175^a	33,139 ± 6,919^ab
SH	4988 ± 192	6207 ± 260^a	5076 ± 195	7499 ± 371^ab
TBARS	1.242 ± 0.036	1.202 ± 0.035	1.400 ± 0.050^a	1.180 ± 0.029^b

Experimental group abbreviations: S sham-operated rat group, S + M sham-operated + meldonium rat group, I/R ischemia/reperfusion rat group, I/R + M ischemia/reperfusion + meldonium rat group. The number of animals per experimental group: n = 8. The data are given as mean ± standard error of the mean. Minimal significant level: p < 0.05. Significantly different: ^ain respect to S group; ^bin respect to I/R group.