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. 2021 Jan 14;11:1305. doi: 10.1038/s41598-020-80011-y

Table 4.

The ascorbic/dehydroascorbic acid ratio (AA/DHA, % of sham) in the serum, liver, and adrenal glands, and adrenal noradrenaline and adrenaline content (µg/mg tissue).

S S + M I/R I/R + M
Liver 100.00 ± 4.58 185.80 ± 10.42a 57.67 ± 4.42a 139.39 ± 7.04ab
Serum 100.00 ± 4.44 197.26 ± 17.02a 24.22 ± 2.67a 50.25 ± 2.17ab
Adrenal 100.00 ± 12.87 290.09 ± 19.38a 187.09 ± 13.74a 176.34 ± 8.46a
Noradrenaline 0.340 ± 0.011 2.185 ± 0.105a 0.098 ± 0.014a 0.088 ± 0.013a
Adrenaline 1.244 ± 0.048 1.068 ± 0.061 0.789 ± 0.076a 0.617 ± 0.058a

Experimental group abbreviations: S sham-operated rat group, S + M sham-operated + meldonium rat group, I/R ischemia/reperfusion rat group, I/R + M ischemia/reperfusion + meldonium rat group. The number of animals per experimental group: n = 8. The data are given as mean ± standard error of the mean. Minimal significant level: p < 0.05. Significantly different: ain respect to S group; bin respect to I/R group.