Table 4.
S | S + M | I/R | I/R + M | |
---|---|---|---|---|
Liver | 100.00 ± 4.58 | 185.80 ± 10.42a | 57.67 ± 4.42a | 139.39 ± 7.04ab |
Serum | 100.00 ± 4.44 | 197.26 ± 17.02a | 24.22 ± 2.67a | 50.25 ± 2.17ab |
Adrenal | 100.00 ± 12.87 | 290.09 ± 19.38a | 187.09 ± 13.74a | 176.34 ± 8.46a |
Noradrenaline | 0.340 ± 0.011 | 2.185 ± 0.105a | 0.098 ± 0.014a | 0.088 ± 0.013a |
Adrenaline | 1.244 ± 0.048 | 1.068 ± 0.061 | 0.789 ± 0.076a | 0.617 ± 0.058a |
Experimental group abbreviations: S sham-operated rat group, S + M sham-operated + meldonium rat group, I/R ischemia/reperfusion rat group, I/R + M ischemia/reperfusion + meldonium rat group. The number of animals per experimental group: n = 8. The data are given as mean ± standard error of the mean. Minimal significant level: p < 0.05. Significantly different: ain respect to S group; bin respect to I/R group.