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. 2021 Jan 14;11:1305. doi: 10.1038/s41598-020-80011-y

Table 5.

The serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) activities (IU/L).

S S + M I/R I/R + M
ALT 46.33 ± 2.49 30.25 ± 1.05a 775.21 ± 51.47a 546.75 ± 31.77ab
AST 76.17 ± 4.05 62.60 ± 2.59a 1,311.00 ± 184.36a 1,107.36 ± 99.67a
ALP 71.83 ± 3.09 49.40.25 ± 3.33a 116.50 ± 10.50a 112.00 ± 8.83a

Experimental group abbreviations: S sham-operated rat group, S + M sham-operated + meldonium rat group, I/R ischemia/reperfusion rat group, I/R + M ischemia/reperfusion + meldonium rat group. The number of animals per experimental group: n = 8. The data are given as mean ± standard error of the mean. Minimal significant level: p < 0.05. Significantly different: ain respect to S group; bin respect to I/R group.