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. 2021 Jan 14;11:1320. doi: 10.1038/s41598-020-80132-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Modeling the CN neuronal circuitry and synaptic currents (excitatory and inhibitory) for edge indentation stimulus. (A) The primary afferents make excitatory synaptic connections with both PN and IN sub-populations. Their synaptic types are indicated by red (excitatory) and blue (inhibitory) triangles. Input currents of 100 PNs when full (B) and partial (C) inhibition comes from INs to PNs while edge stimulus indents the mechanoreceptor grid. Two peaks in the current traces are generated by the onset and end of the indentation profile. (D) Performance of the spiking network when the amount of lateral inhibition is increased within the CN model.