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. 2021 Jan 14;11:1429. doi: 10.1038/s41598-020-80734-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Confirmatory factor analysis clustered PAE-sensitive _exmiRNAs into factors associated with distinct developmental pathways. Structural equation modeling of _exmiRNA loading into the 3-factor solutions at (a) T_2wk and (b) T_6.5mo. Factors are named based on IPA analysis of the canonical pathways and disease and biofunctions for the mRNAs targeted by the miRNAs within each factor (see Supplementary Fig. 6, 8). Figures were constructed using Inspiration (version 9.2.4).