Table 2.

Incidence Rate and Hazard Ratio of NTS Infection.

Variables	NTS infection			cHR	(95% CI)	aHR†	(95% CI)
	n	PY	IR
Bowel resection
No	37	192,902	1.92	1.00	–	1.00	–
Yes	56	188,270	2.97	1.56	(1.03, 2.37)*	1.64	(1.08, 2.48)*
Small bowel resection
No	37	192,902	1.92	1.00	–	1.00	–
Yes	29	79,213	3.66	1.93	(1.18, 3.14)**	1.96	(1.20, 3.19)**
Large bowel resection
No	37	192,902	1.92	1.00	–	1.00	–
Yes	28	98,288	2.85	1.52	(0.93, 2.48)	1.59	(0.97, 2.60)
Right hemicolectomy
No	37	192,902	1.92	1.00	–	1.00	–
Yes	12	36,091	3.32	1.77	(0.92, 3.39)	1.96	(1.02, 3.77)*
Transverse colon resection
No	37	192,902	1.92	1.00	–
Yes	0	2847	0.00	0.00
Left hemicolectomy
No	37	192,902	1.92	1.00	–	1.00	–
Yes	6	12,670	4.74	2.51	(1.06, 5.95)*	2.12	(0.89, 5.04)
Sigmoidectomy
No	37	192,902	1.92	1.00	–	1.00	–
Yes	6	16,997	3.53	1.84	(0.78, 4.37)	1.66	(0.70, 3.96)
Total colectomy
No	37	192,902	1.92	1.00	–
Yes	0	3392	0.00	0.00
Bowel anastomosis
No	37	192,902	1.92	1.00	–	1.00	–
Yes	11	57,857	1.90	1.01	(0.52, 1.99)	1.18	(0.60, 2.33)
Gender
Female	34	174,426	1.95	1.00	–
Male	59	206,746	2.85	1.48	(0.97, 2.26)
Age, year
18–30	2	43,760	0.46	1.00	–	1.00	–
31–40	12	53,443	2.25	4.86	(1.09, 21.7)*	4.71	(1.05, 21.1)*
41–50	6	70,720	0.85	1.83	(0.37, 9.07)	1.67	(0.34, 8.31)
> 50	73	213,249	3.42	7.36	(1.81, 30.0)**	5.25	(1.27, 21.8)*
Occupation
Officer	38	174,857	2.17	1.00	–
Worker	16	88,397	1.81	0.83	(0.47, 1.50)
Farmer	1	7159	1.40	0.65	(0.09, 4.70)
Fisher	21	65,542	3.20	1.48	(0.87, 2.51)
Others	17	45,218	3.76	1.73	(0.98, 3.06)
Comorbidities
Hypertension
No	53	292,983	1.81	1.00	–	1.00	–
Yes	40	88,190	4.54	2.48	(1.64, 3.75)***	1.61	(1.00, 2.58)*
Diabetes
No	72	332,861	2.16	1.00	–	1.00	–
Yes	21	48,312	4.35	1.98	(1.22, 3.23)**	1.28	(0.76, 2.14)
Hyperlipidemia
No	84	358,349	2.34	1.00	–
Yes	9	22,823	3.94	1.66	(0.84, 3.31)
Coronary artery disease
No	79	347,841	2.27	1.00	–	1.00	–
Yes	14	33,332	4.20	1.82	(1.03, 3.21)*	0.92	(0.50, 1.70)
Cerebrovascular accident
No	85	353,319	2.41	1.00	–
Yes	8	27,854	2.87	1.16	(0.56, 2.41)
Chronic kidney disease
No	86	373,043	2.31	1.00	–	1.00	–
Yes	7	8130	8.61	3.62	(1.67, 7.85)**	2.35	(1.06, 5.21)*
COPD
No	80	362,642	2.21	1.00	–	1.00	–
Yes	13	18,530	7.02	3.12	(1.73, 5.61)***	2.18	(1.18, 4.02)*
Chronic liver disease
No	88	366,101	2.40	1.00	–
Yes	5	15,071	3.32	1.35	(0.55, 3.34)
Autoimmune disease
No	89	377,224	2.36	1.00	–	1.00	–
Yes	4	3948	10.13	4.26	(1.56, 11.59)**	3.83	(1.4, 10.47)**
Psoriasis
No	93	380,403	2.44	1.00	–
Yes	0	770	0.00	0.00
Vasculitis
No	93	380,965	2.44	1.00	–
Yes	0	207	0.00	0.00
IBD
No	91	372,731	2.44	1.00	–
Yes	2	8442	2.37	0.98	(0.24, 3.97)

NTS nontyphoidal salmonella, COPD chronic obstructive pulmonary disease, IBD Inflammatory bowel disease, PY person-year, IR incidence rate per 10,000 person-year, cHR crude hazard ratio, aHR adjusted hazard ratio.

^†Adjusted by age, hypertension, diabetes, coronary artery disease, chronic kidney disease, COPD and rheumatoid autoimmune disease.

*p value < 0.05; **p value < 0.01; ***p value < 0.001.