Table 3.
The Stratification Analysis of NTS Infection.
| Variables | Without bowel resection | With bowel resection | cHR | (95% CI) | aHR† | (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | PY | IR | n | PY | IR | |||||
| Gender | ||||||||||
| Female | 14 | 88,765 | 1.58 | 20 | 85,661 | 2.33 | 1.51 | (0.76, 3.00) | 1.61 | (0.81, 3.19) |
| Male | 23 | 104,137 | 2.21 | 36 | 102,609 | 3.51 | 1.59 | (0.94, 2.68) | 1.63 | (0.96, 2.75) |
| Age, year | ||||||||||
| 18–30 | 1 | 22,053 | 0.45 | 1 | 21,707 | 0.46 | 1.07 | (0.07, 17.1) | 1.71 | (0.10, 30.2) |
| 31–40 | 3 | 27,077 | 1.11 | 9 | 26,366 | 3.41 | 3.19 | (0.86, 11.8) | 3.66 | (0.94, 14.2) |
| 41–50 | 3 | 35,047 | 0.86 | 3 | 35,674 | 0.84 | 0.97 | (0.19, 4.80) | 1.07 | (0.21, 5.34) |
| > 50 | 30 | 108,726 | 2.76 | 43 | 104,523 | 4.11 | 1.49 | (0.93, 2.38) | 1.54 | (0.96, 2.45) |
| Occupation | ||||||||||
| Officer | 14 | 86,403 | 1.62 | 24 | 88,454 | 2.71 | 1.70 | (0.88, 3.28) | 1.77 | (0.92, 3.43) |
| Worker | 8 | 45,223 | 1.77 | 8 | 43,174 | 1.85 | 1.03 | (0.38, 2.75) | 1.07 | (0.40, 2.88) |
| Farmer | 0 | 3893 | 0.00 | 1 | 3266 | 3.06 | ||||
| Fisher | 9 | 33,987 | 2.65 | 12 | 31,554 | 3.80 | 1.44 | (0.60, 3.41) | 1.44 | (0.61, 3.43) |
| Others | 6 | 23,397 | 2.56 | 11 | 21,821 | 5.04 | 2.01 | (0.74, 5.44) | 2.02 | (0.75, 5.47) |
| Comorbidities | ||||||||||
| Hypertension | ||||||||||
| No | 16 | 145,886 | 1.10 | 37 | 147,097 | 2.52 | 2.31 | (1.28, 4.15)** | 2.34 | (1.3, 4.22)** |
| Yes | 21 | 47,017 | 4.47 | 19 | 41,173 | 4.61 | 1.04 | (0.56, 1.93) | 1.07 | (0.58, 2.00) |
| Diabetes | ||||||||||
| No | 24 | 167,344 | 1.43 | 48 | 165,517 | 2.90 | 2.04 | (1.25, 3.33)** | 2.11 | (1.29, 3.46)** |
| Yes | 13 | 25,559 | 5.09 | 8 | 22,753 | 3.52 | 0.70 | (0.29, 1.68) | 0.74 | (0.30, 1.78) |
| Hyperlipidemia | ||||||||||
| No | 30 | 179,471 | 1.67 | 54 | 178,879 | 3.02 | 1.82 | (1.16, 2.84)** | 1.91 | (1.22, 2.98)** |
| Yes | 7 | 13,432 | 5.21 | 2 | 9392 | 2.13 | 0.41 | (0.09, 2.00) | 0.37 | (0.08, 1.78) |
| Coronary artery disease | ||||||||||
| No | 29 | 174,143 | 1.67 | 50 | 173,698 | 2.88 | 1.74 | (1.10, 2.75)* | 1.82 | (1.15, 2.88)* |
| Yes | 8 | 18,759 | 4.26 | 6 | 14,572 | 4.12 | 0.96 | (0.33, 2.76) | 0.90 | (0.31, 2.58) |
| Cerebrovascular accident | ||||||||||
| No | 34 | 176,656 | 1.92 | 51 | 176,663 | 2.89 | 1.51 | (0.98, 2.33) | 1.59 | (1.03, 2.46)* |
| Yes | 3 | 16,247 | 1.85 | 5 | 11,607 | 4.31 | 2.34 | (0.56, 9.79) | 2.21 | (0.53, 9.27) |
| Chronic kidney disease | ||||||||||
| No | 35 | 188,352 | 1.86 | 51 | 184,691 | 2.76 | 1.50 | (0.97, 2.30) | 1.56 | (1.01, 2.39)* |
| Yes | 2 | 4551 | 4.39 | 5 | 3579 | 13.97 | 3.19 | (0.62, 16.5) | 2.63 | (0.50, 13.8) |
| COPD | ||||||||||
| No | 29 | 182,097 | 1.59 | 51 | 180,545 | 2.82 | 1.78 | (1.13, 2.82)* | 1.85 | (1.17, 2.93)** |
| Yes | 8 | 10,806 | 7.40 | 5 | 7725 | 6.47 | 0.86 | (0.28, 2.62) | 0.87 | (0.28, 2.70) |
| Chronic liver disease | ||||||||||
| No | 35 | 184,434 | 1.90 | 53 | 181,667 | 2.92 | 1.55 | (1.01, 2.37)* | 1.62 | (1.05, 2.48)* |
| Yes | 2 | 8468 | 2.36 | 3 | 6603 | 4.54 | 1.95 | (0.33, 11.7) | 1.88 | (0.31, 11.3) |
| Autoimmune disease | ||||||||||
| No | 37 | 190,628 | 1.94 | 52 | 186,596 | 2.79 | 1.45 | (0.95, 2.21) | 1.51 | (0.99, 2.31) |
| Yes | 0 | 2274 | 0.00 | 4 | 1674 | 23.89 | ||||
| Psoriasis | ||||||||||
| No | 37 | 192,392 | 1.92 | 56 | 188,011 | 2.98 | 1.56 | (1.03, 2.37)* | 1.51 | (0.99, 2.31) |
| Yes | 0 | 510 | 0.00 | 0 | 259 | 0.00 | ||||
| Vasculitis | ||||||||||
| No | 37 | 192,762 | 1.92 | 56 | 188,204 | 2.98 | 1.56 | (1.03, 2.37)* | 1.64 | (1.08, 2.48)* |
| Yes | 0 | 141 | 0.00 | 0 | 67 | 0.00 | ||||
| IBD | ||||||||||
| No | 37 | 188,948 | 1.96 | 54 | 183,783 | 2.94 | 1.52 | (1.00, 2.3) | 1.59 | (1.04, 2.42)* |
| Yes | 0 | 3955 | 0.00 | 2 | 4487 | 4.46 | ||||
NTS nontyphoidal salmonella, COPD chronic obstructive pulmonary disease, IBD inflammatory bowel disease, PY person-year, IR incidence rate per 10,000 person-year, cHR crude hazard ratio, aHR adjusted hazard ratio.
†Adjusted by age, hypertension, diabetes, coronary artery disease, chronic kidney disease, COPD and rheumatoid autoimmune disease.
*p value < 0.05, **p value < 0.01, ***p value < 0.001.