Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 14;11:1359. doi: 10.1038/s41598-020-80451-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Human serum interference with secreted Gaussia luciferase. Fold change was determined at t_max of each specific reporter system. NFκB-RE reporters were stimulated with different concentrations of HS (5%,10% or 20%) in (A) SW1353 cells and (B) HeLa cells. NFκB-RE reporters were stimulated with IL1β (1 ng/mL) with or without supplementation of 10% HS. Fold change of (C) NFκB-reporters in SW1353 cells and (D) NFκB-reporters in HeLa cells. Percentage inhibition of stimulation with IL1β in combination with HS compared to IL1 β stimulation alone was determined in (E) SW1353 cells and (F) HeLa cells. HS; Human Serum. Data represents mean ± SD of four biological replicates. **p. value ≤ 0.01,***p. value ≤ 0.001.