Figure 7.

Examples of IRE and Different H-FIRE Pulse Waveforms: (a) IRE treatments deliver a series of long-duration monopolar pulses. (b) H-FIRE treatments typically deliver multiple bursts containing $0.25\mathrm{\mu }\text{s}$ and $5\mathrm{\mu }\text{s}$ alternating polarity pulses. Example waveforms showing the first $10\mathrm{\mu }\text{s}$ of a (c) $2\mathrm{\mu }\text{s}$ monopolar, (d) asymmetric $2\mathrm{\mu }\text{s}$, $1\mathrm{\mu }\text{s}$ and $0.25\mathrm{\mu }\text{s}$ (positive–delay–negative), and (e) symmetric $2\mathrm{\mu }\text{s}$, $1\mathrm{\mu }\text{s}$ and $2\mathrm{\mu }\text{s}$ (positive–delay–negative) H-FIRE bursts. Figure reproduced from Sano et al.²⁷.