Table 2.
Effect of Ellagic acid treatment on kidney weight, antioxidants and MDA in HTH against lead acetate induced nephrotoxicity.
| Treatment | Kidney Tissue Homogenate (Units/mg of protein) |
Kidney weight (gm) | Histological Score | |||
|---|---|---|---|---|---|---|
| SOD | CATALASE | GSH | MDA (nmol/g tissue) | |||
| Negative control | 32.41 ± 1.22 | 46.78 ± 0.57 | 8.10 ± 0.29 | 132.54 ± 2.18 | 0.87 ± 0.01 | 0.5 ± 0.12 |
| Positive control | 13.89 ± 0.82∗∗∗ | 21.61 ± 1.29∗∗∗ | 1.94 ± 0.12∗∗∗ | 207.12 ± 2.63∗∗∗ | 1.08 ± 0.3∗∗∗ | 2.71 ± 0.17 |
| EA 50 | 30.31 ± 0.59### | 39.74 ± 0.76### | 6.83 ± 0.06### | 148.90 ± 3.45### | 0.91 ± 0.01### | 0.89 ± 0.21 |
| EA 25 | 23.74 ± 1.26### | 32.54 ± 1.25### | 5.83 ± 0.05### | 157.46 ± 2.35### | 0.93 ± 0.02### | 1.35 ± 0.23 |
All values are mean ± SEM, n = 8, ∗∗∗P < 0.001 when compared to Negative control; ###P < 0.001 compared to Positive control group. EA 50: Ellagic acid (50 mg/kg) EA 25: Ellagic acid (25 mg/kg).