Fig. 11.

(A) Mulrooney et al. [63] has depicted that relative expression of NF-$\kappa$B significantly increases in cancer (CT-2A astrocytoma) compared to normal ones. (B) Our computational results show similar behavior of NF-$\kappa$B in cancer cells compared to that in normal ones. (C) Higher expression of PI3K has been captured in the in vivo/in vitro experiment performed by Zhang et al. [55] in the case of colon cancer as compared to the normal tissue samples, (D) Similar difference in the expression levels of PI3K in cancer and normal cells have been captured by the proposed computational model, (E) mTOR expression is higher in colon cancer compared to normal one as per the in vivo/in vitro experiment performed by Zhang et al. [55], and (F) Similar altered behavior of mTOR can be found in our computational results.