Table 2.

Change from baseline in body weight and fasting blood glucose in the intent to treat population.

	12:12 Schedule	14:10 Schedule	LS mean difference
ITT Population	(n = 39)	(n = 39)
Baseline body weight (kg)	121.7 ± 20	125.1 ± 21.2	–
95% CI	(115.3, 128.1)	(118.3, 131.9)
Week 8 body weight (kg)	113.4 ± 19.9	115.3 ± 20.8	–
95% CI	(107.1, 119.8)	(108.6, 121.9)
Week 8 change in body weight (kg)	−8.4 ± 5.4	−10.0 ± 5.1	1.6 ± 5.2
95% CI	(−10.1, −6.7)	(−11.6, −8.4)	(−0.1, 3.2)
P value	<0.0001	<0.0001	0.063
Week 8 change in body weight (%)	−6.6 ± 4.7	−7.8 ± 4.3	1.2 ± 4.5
95% CI	(−8.1, −5.1)	(−9.2, −6.4)	(−0.2, 2.7)
P value	<0.0001	<0.0001	0.094
Baseline FBG (mg/dl)	102.6 ± 32.4	103.8 ± 29.5	–
95% CI	(92.2, 112.9)	(94.3, 113.2)
Week 8 FBG (mg/dl)	98.1 ± 16.8	96.0 ± 15.4	–
95% CI	(92.7, 103.5)	(91.0, 100.9)
Week 8 change in FBG (mg/dl)	−3.4 ± 21.2	−8.0 ± 23.3	4.6 ± 23.5
95% CI	(−10.2, 3.5)	(−15.5, −0.5)	(−2.9, 12.1)
P value	0.33	0.037	0.22

Data are LS mean ± SD. The intent to treat population includes all randomized participants. Missing data were imputed using the last observation carried forward method.

FBG fasting blood glucose.