Table 2.

Clinical Characteristics of Patients With Idiopathic Subglottic Stenosis and Paired Affected Family Members.

Pair/group: relationship	Sex	Birth year	Onset year	Onset age, y	Anticipation present?	Difference in year of onset, y	Relative difference in age of onset, y	Dilation interval, mo
1
Daughter	F	1971	2008	37	Y	4	−18	38
Mother	F	1949	2004	55				7.5
2
Daughter	F	1970	2011	41	Y	9	−1
Mother	F	1950	1992	42				6
Paternal cousin	F
Daughter of paternal cousin	F
3
Daughter	F	1974	2015	41	Y	3	−15
Mother	F	1956	2012	56				6.3
4
Sister	F	1980	2016	36	NA	3	NA
Sister	F	1981	2013	32				4.7
5
Daughter	F	1978	2008	30	Y	4	−22
Father	M	1952	2004	52				6
6
Daughter	F	1969	2014	45	N		+2
Mother	F			43
7
Daughter	F
Mother	F
8
Daughter	F	1979	2005	26	Y	5	−22
Father	M	1952	2000	48
9
Daughter	F	1956	2012	56	Y	22	−2
Mother	F	1932	1990	58				51
10
Daughter	F	1950	2005	55	N	35	+12
Mother	F	1927	1970	43
11
Daughter	F	1973	2016	43
Mother	F
12
Niece	F	1973	2013	40	NA			3.5
Maternal aunt	F
Cousin	F
13
Paternal aunt	F	1979	2013	34	NA			9
Niece	F
14
Sister	F	1963	2005	42	NA	2
Sister	F	1965	2007	42				16.8
15
Daughter	F	1998	2012	14	Y	2	−40	2.6
Mother	F	1960	2014	54				6.5
16
Daughter	F	1977	2005	33	Y	13	−4
Mother	F	1955	1992	37				72
17
Daughter	F	1952	1994	42				39.4
Mother	F
18
Daughter	F	1985	2017	32	Y	26	−1	5.3
Daughter	F	1987	2011	24	Y	20	−9	15.8
Mother	F	1957	1991	33				22.4
19
Daughter	F	1965	2000	35	Y	11	−40
Mother	F	1936	2011	75
20
Sister	F
Sister	F
Mean ± SD				42.6 ± 11.8	84.6%	8.9 ± 10.9	−12.3 ± 15.8	18.4 ± 20.0

Abbreviation: NA, not applicable.