Skip to main content
. 2021 Jan 9;14:100293. doi: 10.1016/j.ynstr.2021.100293

Fig. 3.

Fig. 3

Effects of the FST on mPFC dialysate DA and 5-HT levels in WT mice treated with selective inhibitors of FAAH and MAGL. Microdialysis experiment expressing DA levels as the percentage change from baseline levels (mean ± SEM) (A). The AUC for DA summarizes the effect of the FST on dialysate DA (mean ± SEM) (B). Microdialysis experiment expressing 5-HT levels as the percentage change from baseline levels (mean ± SEM) (C). The AUC for 5-HT summarizes the effect of the FST on dialysate DA (mean ± SEM) (D). The drug injection is indicated by the arrow. FAAH inhibitor [PF-3845, 3 mg/kg (i.p.)], MAGL inhibitor [(JZL184, 10 mg/kg (i.p.)] or vehicle were administered in groups of 7–8 mice. (*)p < 0.05 denotes significant differences vs. the vehicle group. (a)p < 0.05 denotes significant differences vs. the PF-3845 group. (+)p < 0.05 denotes significant differences vs. baseline levels (100%).