Table 2. Genetic association models for the study variants.
| Genotype | Female | Male | OR (95% CI) | P-value | |
|---|---|---|---|---|---|
| rs855791 | |||||
| Heterozygote comparison | A/A | 10 (56) | 98 (55) | 1.00 | 0.95 |
| A/G | 8 (44) | 81 (45) | 1.03 (0.39–2.74) | ||
| Allelic model | A | 28 (78) | 277 (77) | 1.00 | 0.95 |
| G | 8 (22) | 81 (23) | 1.02 (0.44–2.33) | ||
| rs9357271 | |||||
| Co-dominant model | T/T | 10 (55.6) | 72 (40.2) | 1.00 | 0.29 |
| C/T | 7 (38.9) | 78 (43.6) | 1.55 (0.56–4.28) | ||
| C/C | 1 (5.6) | 29 (16.2) | 4.03 (0.49–32.90) | ||
| Dominant model | T/T | 10 (55.6) | 72 (40.2) | 1.00 | 0.21 |
| C/T-C/C | 8 (44.4) | 107 (59.8) | 1.86 (0.70–4.93) | ||
| Recessive model | T/T-C/T | 17 (94.4) | 150 (83.8) | 1.00 | 0.18 |
| C/C | 1 (5.6) | 29 (16.2) | 3.29 (0.42–25.67) | ||
| Over-dominant model | T/T-C/C | 11 (61.1) | 101 (56.4) | 1.00 | 0.70 |
| C/T | 7 (38.9) | 78 (43.6) | 1.21 (0.45–3.27) | ||
| Allelic model | T | 27 (75) | 222 (62) | 1.00 | |
| C | 9 (25) | 136 (38) | 1.83 (0.83–4.02) | 0.12 | |
| Log-additive | — | — | — | 1.77 (0.82–3.82) | 0.13 |
Values are shown as number (percentage). Chi-square or Fisher’s exact tests were used. Abbreviation: OR (95% CI), odds ratio and confidence interval.