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. 2021 Jan 14;41(1):BSR20203130. doi: 10.1042/BSR20203130

Figure 7. Circ_0061012 up-regulates the level of GAB1 through sponging miR-194-5p in IL-22-induced HaCaT cells.

Figure 7

(A,B) The mRNA and protein levels of GAB1 were measured in HaCaT cells treated with IL-22, IL-22 + si-NC, IL-22 + si-circ_0061012, IL-22 + si-circ_0061012 + anti-miR-NC or IL-22 + si-circ_0061012 + anti-miR-194-5p by qRT-PCR and Western blot assay. (C) The diagram revealed that circ_0061012 accelerated psoriasis progression through miR-194-5p/GAB1 axis. The experiments were independently repeated for three times with at least three technical repetitions. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.