Table 1. Characteristics of studies included in the meta-analysis.
Study | Year | Country | Cancer type | Detection method | Sample size | LncRNA FTX expression | Survival information | NOS score | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High | Low | ||||||||||||||||||||
Total | LNM | DM | HS | LD | Larger TS | M | Total | LNM | DM | HS | LD | Larger TS | M | ||||||||
Zhao et al. [9] | 2020 | China | CRC | RT-qPCR | 30 | 15 | 9 | 11 | 10 | NA | 10 | 9 | 15 | 6 | 7 | 7 | NA | 6 | 7 | NA | 8 |
He et al. [12] | 2017 | China | RCC | RT-qPCR | 150 | 82 | 63 | NA | 65 | NA | 76 | 42 | 68 | 30 | NA | 34 | NA | 48 | 37 | NA | 8 |
Liu et al. [13] | 2016 | China | HCC | RT-qPCR | 129 | 64 | NA | NA | 16 | 43 | 45 | 51 | 65 | NA | NA | 16 | 56 | 57 | 60 | OS/RFS | 7 |
Li et al. [10] | 2018 | China | OSC | RT-qPCR | 84 | 39 | NA | 17 | 23 | NA | 25 | 22 | 45 | NA | 9 | 14 | NA | 22 | 27 | OS | 9 |
Zhang et al. [11] | 2020 | China | GC | RT-qPCR | 71 | 32 | 25 | NA | 26 | 19 | 17 | 17 | 39 | 21 | NA | 18 | 11 | 18 | 22 | OS | 7 |
Liang et al. [17] | 2020 | China | glioma | RT-qPCR | 187 | 95 | NA | NA | 50 | NA | NA | 40 | 92 | NA | NA | 26 | NA | NA | 49 | OS/PFS | 7 |
Guo et al. [16] | 2015 | China | CRC | RT-qPCR | 187 | 75 | 46 | NA | 44 | 38 | NA | 14 | 112 | 71 | NA | 60 | 51 | NA | 31 | OS | 6 |
Jiang et al. [18] | 2019 | China | GC | RT-qPCR | 93 | 48 | 34 | 15 | 36 | 27 | 35 | 31 | 45 | 26 | 4 | 23 | 6 | 14 | 29 | NA | 9 |
Li et al. [14] | 2019 | China | HCC | RT-qPCR | 73 | 37 | 18 | 18 | NA | 2 | 23 | 27 | 36 | 6 | 6 | NA | 12 | 21 | 20 | OS/DFS | 6 |
Yang et al. [20] | 2018 | China | CRC | RT-qPCR | 80 | 40 | 27 | 25 | 26 | 12 | 26 | 27 | 40 | 15 | 12 | 17 | 14 | 17 | 26 | OS | 8 |
Liu et al. [21] | 2016 | China | HCC | RT-qPCR | 126 | 65 | NA | NA | 18 | 32 | 28 | 50 | 61 | NA | NA | 8 | 12 | 10 | 49 | OS/DFS | 7 |
Abbreviations: CRC, colorectal cancer; DFS, disease-free survival; DM, distant metastasis; GC, gastric cancer; HCC, hepatocellular carcinoma; HS, high TNM/clinical stage (III/IV); Larger TS, the larger tumor size group (diameter ≥3 cm); LD, low differentiation; LNM, lymph node metastasis; M, man; OS, overall survival; NA, not available; NOS, Newcastle–Ottawa scale; OSC, osteosarcoma; PFS, progression-free survival; RCC, renal cell carcinoma; RFS, recurrence-free survival; RT-qPCR, reverse transcription quantitative real-time polymerase chain reaction.