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. 2021 Jan 14;41(1):BSR20203995. doi: 10.1042/BSR20203995

Table 1. Characteristics of studies included in the meta-analysis.

Study Year Country Cancer type Detection method Sample size LncRNA FTX expression Survival information NOS score
High Low
Total LNM DM HS LD Larger TS M Total LNM DM HS LD Larger TS M
Zhao et al. [9] 2020 China CRC RT-qPCR 30 15 9 11 10 NA 10 9 15 6 7 7 NA 6 7 NA 8
He et al. [12] 2017 China RCC RT-qPCR 150 82 63 NA 65 NA 76 42 68 30 NA 34 NA 48 37 NA 8
Liu et al. [13] 2016 China HCC RT-qPCR 129 64 NA NA 16 43 45 51 65 NA NA 16 56 57 60 OS/RFS 7
Li et al. [10] 2018 China OSC RT-qPCR 84 39 NA 17 23 NA 25 22 45 NA 9 14 NA 22 27 OS 9
Zhang et al. [11] 2020 China GC RT-qPCR 71 32 25 NA 26 19 17 17 39 21 NA 18 11 18 22 OS 7
Liang et al. [17] 2020 China glioma RT-qPCR 187 95 NA NA 50 NA NA 40 92 NA NA 26 NA NA 49 OS/PFS 7
Guo et al. [16] 2015 China CRC RT-qPCR 187 75 46 NA 44 38 NA 14 112 71 NA 60 51 NA 31 OS 6
Jiang et al. [18] 2019 China GC RT-qPCR 93 48 34 15 36 27 35 31 45 26 4 23 6 14 29 NA 9
Li et al. [14] 2019 China HCC RT-qPCR 73 37 18 18 NA 2 23 27 36 6 6 NA 12 21 20 OS/DFS 6
Yang et al. [20] 2018 China CRC RT-qPCR 80 40 27 25 26 12 26 27 40 15 12 17 14 17 26 OS 8
Liu et al. [21] 2016 China HCC RT-qPCR 126 65 NA NA 18 32 28 50 61 NA NA 8 12 10 49 OS/DFS 7

Abbreviations: CRC, colorectal cancer; DFS, disease-free survival; DM, distant metastasis; GC, gastric cancer; HCC, hepatocellular carcinoma; HS, high TNM/clinical stage (III/IV); Larger TS, the larger tumor size group (diameter ≥3 cm); LD, low differentiation; LNM, lymph node metastasis; M, man; OS, overall survival; NA, not available; NOS, Newcastle–Ottawa scale; OSC, osteosarcoma; PFS, progression-free survival; RCC, renal cell carcinoma; RFS, recurrence-free survival; RT-qPCR, reverse transcription quantitative real-time polymerase chain reaction.