TABLE 2.

Univariate and multivariate Cox proportional hazards analysis of FOXO4 gene expression and overall survival for patients with gastric cancer

Factor	Univariate analysis		Multivariate analysis
	HR (95% CI)	P	HR (95% CI)	P
Gender	0.780 (0.514‐1.183)	0.242
Age	1.262(0.832‐1.915)	0.273
Diameter	1.254(0.810‐1.941)	0.309
T stage	2.029(1.479‐2.782)	<0.001	1.255(0.815‐1.932)	.303
N stage	1.652(1.365‐2.000)	<0.000	1.356(1.050‐1.750)	.019
Grade	1.694(1.094‐2.625)	0.018	1.169(0.738‐1.851)	.506
Lymphovascular invasion	2.193(1.404‐3.426)	0.001	1.818(1.145‐2.889)	.011
Perineural invasion	1.835(1.193‐2.822)	0.006	1.620(1.040‐2.523)	.033
Tumor location	1.149(0.957‐1.379)	0.137
FOXO4	0.284(0.143‐0.567)	<0.001	0.393(0.191‐0.808)	.011

Abbreviations: CI, confidence interval; HR, hazard ratio.

Bold type indicates statistical significance.