Table 1|.
Patient cohort demographic details, broken down by SARS-CoV-2 infection and disease status
| All patients | SARS-Cov-2 positive (C19+) | Intubated and C19+ | Mortality and C19+ | Macula and C19+ | Complement def. and C19+ | Coagulation and C19+ | Hypertension and C19+ | T2D and C19+ | Obesity and C19+ | CAD and C19+ | Over 65 years and C19+ | Cough (reference) and C19+ | Smokers and C19+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | 11,116 | 6,393 | 484 | 618 | 88 | 4 | 1,239 | 1,988 | 911 | 831 | 1,698 | 2,400 | 725 | 723 |
| Age (IQR) | 52.0 (34.7–69.5) | 57.1 (41.5–72.0) | 62.3 (53.0–73.3) | 76.3 (69.5–86.3) | 74.1 (67.2–84.6) | 57.9 (49.1–70.9) | 61.8 (48.2–77.0) | 66.6 (56.4–78.5) | 67.2 (57.9–78.2) | 57.9 (43.5–71.8) | 66.2 (55.9–79.6) | 77.4 (70.4–83.5) | 59.2 (46.6–72.0) | 63.8 (54.8–74.7) |
| Sex (% male) | 44.8 | 49.7 | 63.4 | 59.2 | 42 | 50 | 42.1 | 48.5 | 52.5 | 32.9 | 49.8 | 52 | 53.4 | 61.4 |
| Past/current smoker (%) | 26.8 | 25.7 | 27.7 | 33.7 | 29.5 | 50 | 26.7 | 30.3 | 32.4 | 23.9 | 31 | 33.8 | 25.5 | 100 |
| Data source historical (%) | 61.7 | 62.9 | 71.3 | 79.6 | 100 | 100 | 97.9 | 98.4 | 97.4 | 98.6 | 96.2 | 65.6 | 81.9 | 79.9 |
| Asian (%) | 2.7 | 2.4 | 0.8 | 0.8 | 0 | 0 | 1.9 | 1.5 | 1.4 | 1 | 1.8 | 1.4 | 1.7 | 0.8 |
| Black/African American (%) | 21.2 | 22.2 | 21.5 | 17.5 | 17 | 25 | 20.2 | 20.9 | 23.8 | 21.4 | 21.1 | 22.9 | 18.2 | 24.5 |
| White (%) | 31.3 | 28.4 | 23.6 | 27.3 | 36.4 | 0 | 34.1 | 30.8 | 27.8 | 29.8 | 33.7 | 31.3 | 28.4 | 31.4 |
| Other (%) | 26.6 | 27.9 | 31 | 32.4 | 28.4 | 50 | 24.4 | 27.5 | 27 | 29.1 | 24.7 | 28.6 | 31 | 24.8 |
| Declined (%) | 18.1 | 19.1 | 23.1 | 22 | 18.2 | 25 | 19.5 | 19.3 | 20 | 18.7 | 18.7 | 15.8 | 20.7 | 18.5 |
| Hispanic (%) | 31.8 | 34.2 | 48.8 | 48.7 | 59.1 | 50 | 49 | 48.5 | 49.6 | 54.3 | 44.3 | 37 | 51 | 35.1 |
| Not Hispanic (%) | 39.5 | 37 | 27.9 | 28.8 | 25 | 25 | 30.9 | 30.6 | 29.2 | 26.5 | 34 | 38 | 25.2 | 40.5 |
| Declined/other (%) | 28.7 | 28.8 | 23.3 | 22.5 | 15.9 | 25 | 20.1 | 20.9 | 21.2 | 19.3 | 21.6 | 25 | 23.7 | 24.3 |
| Hypertension (%) | 28.2 | 31.1 | 43.4 | 60.2 | 89.8 | 100 | 72.2 | 100 | 85.3 | 75.6 | 77.3 | 46.2 | 49.1 | 53.3 |
| T2D (%) | 12.6 | 14.2 | 22.9 | 30.9 | 54.5 | 25 | 34.5 | 39.1 | 100 | 40.2 | 38.2 | 22.3 | 23.3 | 27.2 |
| Obesity (%) | 12 | 13 | 15.9 | 18.6 | 38.6 | 0 | 34.4 | 31.6 | 36.7 | 100 | 31.1 | 13.5 | 20.4 | 18.8 |
| CAD (%) | 26.8 | 26.6 | 41.1 | 55 | 79.5 | 100 | 65.4 | 66 | 71.2 | 63.5 | 100 | 40.6 | 40.3 | 46.9 |
| Mechanical ventilation | 9.2 (8.7–9.8) | 7.6 (6.9–8.2) | 100 (100–100) | 33.0 (29.3–36.7) | 15.9 (8.3–23.6) | 0 (0–0) | 10.2 (8.5–11.9) | 10.6 (9.2–11.9) | 12.2 (10.1–14.3) | 9.3 (7.3–11.2) | 11.7 (10.2–13.2) | 10.1 (8.9–11.3) | 10.5 (8.3–12.7) | 11.1 (8.8–13.4) |
| Mortality | 10.2 (9.7–10.8) | 9.7 (8.9–10.4) | 42.1 (37.7–46.5) | 100 (100–100) | 25.0 (16.0–34.0) | 0 (0–0) | 17.1 (15.0–19.2) | 18.7 (17.0–20.4) | 21.0 (18.3–23.6) | 13.8 (11.5–16.2) | 20.0 (18.1–21.9) | 21.4 (19.7–23.0) | 12.7 (10.3–15.1) | 15.2 (12.6–17.8) |
| Intubation HR (95% CI) / univar. | -- | -- | -- | -- | 2.2 (1.3–3.7)** | -- | 1.5 (1.2–1.8)** | 1.7 (1.5–2.1)** | 1.9 (1.5–2.3)** | 1.3 (1.0–1.7)* | 2.0 (1.7–2.4)** | 1.7 (1.4–2.0)** | 1.5 (1.1–1.9)** | 1.1 (0.9–1.5) |
| Intubation HR (95% CI) / age and sex corr. | -- | -- | -- | -- | 1.8 (1.1–3.1)* | -- | 1.5 (1.2–1.8)** | 1.6 (1.3–1.9)** | 1.6 (1.3–2.0)** | 1.5 (1.1–1.9)** | 1.8 (1.5–2.2)** | 1.3 (1.0–1.8) | 1.4 (1.1–1.8)** | 1.0 (0.7–1.3) |
| Death HR (95% CI) / univar. | -- | -- | -- | -- | 3.0 (2.0–4.6)** | -- | 2.3 (2.0–2.8)** | 3.8 (3.2–4.4)** | 2.9 (2.5–3.5)** | 1.6 (1.3–2.0)** | 3.7 (3.2–4.3)** | 8.8 (7.1–10.9)** | 1.3 (1.1–1.7)* | 1.5 (1.2–1.9)** |
| Death HR (95% CI) / age and sex corr. | -- | -- | -- | -- | 1.5 (1.0–2.3)* | -- | 1.8 (1.5–2.1)** | 2.3 (2.0–2.7)** | 2.0 (1.7–2.4)** | 1.9 (1.6–2.4)** | 2.2 (1.9–2.6)** | 1.7 (1.2–2.3)** | 1.3 (1.1–1.6)* | 1.1 (0.9–1.4) |
C19+, COVID-19 positive; HR, hazard ratio; IQR, interquartile range;
*
P < 0.05,
**
P < 0.001.