Table 3.
Comorbidities |
China
|
North America
|
P
2
value
|
||||||||||
Number of cases (n)1 |
Meta-analysis
|
Heterogenicity
|
Number of cases (n) |
Meta-analysis
|
Heterogenicity
|
||||||||
Frequency (%)
|
95%CI
|
τ
2
|
Q
|
I
2
|
Frequency (%)
|
95%CI
|
τ
2
|
Q
|
I
2
|
||||
Obesity | 666 | 2.1 | 0.1-4.3 | 0.001 | 54 | 91 | 26895 | 22.9 | 18.1-27.9 | 0.016 | 2130 | 99 | < 0.001 |
Hypertension | 22650 | 25.6 | 23.8-27.4 | 0.013 | 2154 | 91 | 34442 | 47.6 | 41.0-54.2 | 0.034 | 5347 | 99 | < 0.001 |
Diabetes | 23770 | 11.8 | 10.9-12.6 | 0.002 | 980 | 79 | 35384 | 34.1 | 30.1-38.2 | 0.015 | 3169 | 98 | < 0.001 |
Cardiovascular diseases | 22439 | 7.9 | 7.1-8.7 | 0.002 | 1339 | 86 | 33459 | 20.8 | 18.4-23.3 | 0.005 | 4379 | 99 | < 0.001 |
COPD | 17263 | 3.3 | 2.8-3.7 | 0.001 | 540 | 78 | 29697 | 11.6 | 10.1-13.1 | 0.001 | 716 | 94 | < 0.001 |
Cancer | 16527 | 9.7 | 7.1-12.2 | 0.017 | 19185 | 99 | 24564 | 6.6 | 5.5-7.6 | 0.001 | 254 | 89 | < 0.001 |
Liver diseases (any) | 11087 | 3.3 | 2.8-3.9 | 0.001 | 276 | 68 | 9706 | 3.1 | 2.1-4.2 | 0.001 | 98 | 83 | 0.414 |
Chronic kidney diseases | 16394 | 2.1 | 1.7-2.4 | 0.001 | 236 | 59 | 30761 | 11.8 | 10.0-13.6 | 0.002 | 1082 | 86 | < 0.001 |
n is the number of subjects assessed for each comorbidity as per the source database[7].
Chi Square test for the difference between prevalence of comorbidity in China and North America. COPD: Chronic obstructive pulmonary disease.