Table 4.
Average levels of biomarkers in coronavirus disease 2019 cases from China and North America
| Biomarker |
China
|
North America
|
P 3 value | Reference range | ||
|
Number of cases (n)1
|
Mean2 (95%CI)
|
Number of cases (n)1
|
Mean2 (95%CI)
|
|||
| White blood cell count (109/L) | 21703 | 5.47 (5.4-5.6) | 9094 | 7.53 (7.51-7.55) | < 0.0001 | 3.4-9.6 |
| Lymphocyte count (109/L) | 22053 | 1.04 (1.0-1.3) | 8653 | 0.88 (0.87-0.89) | < 0.0001 | 0.95-3.07 |
| Aspartate aminotransferase (U/L) | 15495 | 30.8 (30.5-31.3) | 8627 | 45.2 (45.1-45.3) | < 0.0001 | 8-20 |
| Total bilirubin (μmoL/L) | 10824 | 10.7 (10.6-10.8) | 281 | 1.4 (1.1-1.7) | < 0.0001 | 2-17 |
| Creatine kinase (U/L) | 11382 | 85.3 (84.7-85.8) | 9033 | 115 (113-117) | < 0.0001 | M: 25-90 F: 10-70 |
| C-reactive protein (mg/L) | 16144 | 25.9 (25.5-26.4) | 12059 | 116 (115-117) | < 0.0001 | 0-8 |
| Procalcitonin (ng/mL) | 12050 | 2.44 (2.2-2.6) | 11661 | 0.70 (0.68-0.72) | < 0.0001 | 0-0.15 |
1
n is the number of subjects assessed for a given characteristic as per the source database[7].
2
Weighted mean; 3Student’s t-test.