. 2021 Jan 4;21:5. doi: 10.1186/s12879-020-05672-6

Table 7.

Severe who clinical stage 3 for the odyssey trial

Children (< 15 years of age)	Adolescents (≥15 years of age)
• Unexplained moderate malnutrition or wasting not adequately responding to standard therapy • Persistent oral candidiasis (after first 6–8 weeks of life) • Symptomatic lymphoid interstitial pneumonitis • Chronic HIV-associated lung disease including bronchiectasis	• Unexplained severe weight loss (> 10% of presumed or measured body weight) • Persistent oral candidiasis

Children (< 15 years of age)

Adolescents (≥15 years of age)

• Unexplained moderate malnutrition or wasting not adequately responding to standard therapy

• Persistent oral candidiasis (after first 6–8 weeks of life)

• Symptomatic lymphoid interstitial pneumonitis

• Chronic HIV-associated lung disease including bronchiectasis

• Unexplained severe weight loss (> 10% of presumed or measured body weight)

• Persistent oral candidiasis

Reference: World Health Organization. WHO case definitions of HIV for surveillance, and revised clinical staging and immunological classification of HIV related disease in adults and children. Geneva: World Health Organization; 2007