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. 2021 Jan 15;14:13. doi: 10.1186/s13041-021-00732-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — mPFC neurons exhibit a differential pattern of cross-modal interaction. a The comparison of the index of cross-modal interaction (MI) between low (3 kHz) and high (10 kHz) tone conditions for neurons with showing cross-modal facilitation in VA_3k condition. MI is calculated by the following function: MI = (R_VA—R_A) / (R_VA + R_A); where R_VA and R_A represent the mean response in multisensory and auditory alone trials, respectively. Paired gray circles connected with a gray line represent one neuron’s responses. Dark circles represent the mean MI across neurons. **, p < 0.001. Similarly, b shows MI comparisons for neurons with showing cross-modal facilitation in VA_10k condition. c, d shows the mean PSTHs of different cue trials for the same two groups of neurons shown in a and b, demonstrating greater responsiveness in the multisensory stimulation containing the preferred auditory stimulus