Table 1.
Results of the physical examinations and laboratory tests at the initial evaluation
| Symptom/Sign/Lab test | No. positive (Percent) | Comments |
|---|---|---|
| Oral lesions | 219 (92%) | Most common: ≤3 round lip lesions, 1-5 mm in size |
| Ocular lesions | 105 (44.1%) | Posterior uveitis was the most common pathology (49 patients), followed by anterior uveitis (25 patients) |
| Genital lesions | 87 (36.6%) | |
| Articular involvement | 38 (16%) | Mechanical joint pain was more common than inflammatory arthritis |
| Gastrointestinal | 31 (13%) | Diarrhea was the most common symptom (15 patients), followed by nausea, and rectorrhagia |
| Neurologic involvement | 17 (7.3%) | Seizure was the most common (9 patients) |
| Erythema Nodosum | 15 (6.3%) | |
| Cardiovascular | 13 (5.6%) | DVT in 5 patients and pulmonary thromboembolism in 3 patients |
| Pseudofolliculitis | 4 (1.7%) | |
| Positive Pathergy reaction | 30 (12.6%) | A positive pathergy reaction was the reason for referral in 5 patients |
| Human Leukocyte antigens | ||
| HLA-B5 | 138 (58%) | |
| HLA-B51 | 114 (47.9%) | A positive HLA-B51 antigen was the primary reason for referral in 35 patients |
| HLA-B27 | 15 (6.3%) | |
Note that total is > 100% due to multi-organ involvement
DVT Deep-vein thrombosis, HLA Human leukocyte antigen