Table 2.
Clinical variables and psychopharmacological treatment in OCD patients, with or without MDD comorbidity
| OCD without MDD (N = 35) |
OCD with MDD (N = 26) |
Statistic | df | P value | |
|---|---|---|---|---|---|
| Clinical Variables | |||||
| HAM-D-17 | 6.67 (4.22) | 10.04 (5.87) | t = −2.62 | 59 | 0.01* |
| Y-BOCS | 22.55 (6.06) | 22.13 (4.46) | t = 0.29 | 59 | 0.77 |
| STAI-Trait | 35.11 (9.82) | 34.7 (13.50) | t = 0.14 | 59 | 0.89 |
| STAI-State | 26.40 (14.40) | 26.04 (16.11) | t = 0.09 | 59 | 0.93 |
| Psychopharmacological Treatment Doses (DDD) | |||||
| SSRI | 3 (1.80) | 3.12 (2.44) | t = −0.21 | 59 | 0.83 |
| Dual-action antidepressants | 0.09 (0.35) | 0.38 (0.91) | t = −1.72 | 59 | 0.09 |
| TCA | 0.66 (0.91) | 0.65(0.90) | t = 0.07 | 59 | 0.95 |
| Other antidepressants | 0.01 (0.08) | 0.04 (0.20) | t = −0.65 | 59 | 0.52 |
| Benzodiazepines (diazepam equivalents mg/day) | 3.47 (6.75) | 8.44 (9.35) | t = −2.41 | 59 | 0.02* |
| Antipsychotics (chlorpromazine equivalents mg/day) | 64.86 (116.22) | 52.31 (109.70) | t = 0.43 | 59 | 0.67 |
Data are mean (SD). Abbreviations: OCD Obsessive-Compulsive Disorder, MDD Major Depressive Disorder, HAM-D Hamilton Depression Rating Scale, Y-BOCS Yale-Brown Obsessive Compulsive Scale, STAI State-Trait Anxiety Inventory, DDD defined daily doses, SSRI selective serotonin reuptake inhibitors, TCA tricyclic antidepressants
*P < 0.05