Figure 4.
Dwell times (ton) and jump lengths (J) at varying [ATP]. (A) Dwell times identified before the jump at varying [ATP]. Green diamonds, RLC-LMM cofilaments, 5 µM ATP, n = 9; 7.5 µM ATP, n = 50; 10 µM ATP, n = 45; 12.5 µM ATP, n = 46; 15 µM ATP, n = 12; 20 µM ATP, n = 11. Red diamonds, LMM-LMM cofilaments, 10 µM ATP, n = 16. The asterisks for the 10 µM ATP condition indicate the two means are statistically significantly different using a two-sample t test with P = 0.000645. The black line is a fit of Eq. 1 to the means. (B) Jump lengths (J) following the dwell times identified in A. The asterisks for the 10 µM ATP data indicate the means are statistically significantly different with P = 0.01. For A and B, the black vertical whiskers indicate SEM; the longer black horizontal line is the mean.