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. 2021 Jan 13;153(2):e202012731. doi: 10.1085/jgp.202012731

Figure 2.

Figure 2.

Impact of cholesterol in phosphatidylcholine bilayers on KcvS function. (A) Representative channel fluctuations of KcvS at +120 mV (top) and −120 mV (bottom) in a pure DPhPC bilayer (0% cholesterol) and in a DPhPC bilayer with 30 mol% cholesterol. Closed (C) and open (O) levels are indicated. (B and C) Open channel current/voltage (I/V) relations (B) and PO/V relations (C) in the absence (black) and presence of 30 mol% cholesterol (red). Data are mean ± SD of n = 10 (0% cholesterol) and n = 4 (30 mol% cholesterol) independent measurements.