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. 2021 Jan 13;153(2):e202012731. doi: 10.1085/jgp.202012731

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© 2021 Winterstein et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure S2. — Impact of cholesterol in phosphatidylcholine bilayers on Kcv_NTS and Kmpv_12T function. (A–F) Representative fluctuations at ±120 mV in a pure DPhPC bilayer (0% Chol) and in DPhPC bilayer with 30 mol% cholesterol (30% Chol) from Kcv_NTS (A) and Kmpv_12T (D). Closed (C) and open (O) levels are indicated. I/V relations (B and E) and P_O/V relations (C and F) of the respective channels on top in absence (black) and presence (red) of 30 mol% Chol. Data are mean ± SD of n = 6/4 and n = 10/3 measurements with Kcv_NTS and Kmpv_12T in the absence/presence of cholesterol, respectively. Chol, cholesterol.